Information and National Guidance minister, Maj Gen Jim Muhwezi, has accepted defeat in Rujumbura constituency race in Rukungiri district.
Muhwezi was defeated by Forum for Democratic Change [FDC] candidate, Fred Tumuheirwe, losing the seat he has held for over 30 years.
Muhwezi, who is among the 17 ministers who were defeated, has accepted the outcomes of the elections.
He, however, cited irregularities in the poll.
His wife, Susan Muhwezi, asked the people of Rukungiri to stay united.
She asked the new MP to promote unity, peace and serve the people diligently.
In other results, Matsiko Winfrey won the Rukungiri woman MP seat.
Roland Mugume won the Rukungiri municipality seat.
Paula Turyahikayo won the Rubabo constituency seat.